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Sikandar G Khan Selected Research

Trichothiodystrophy Syndromes

10/2021Metronidazole-Induced Hepatitis in a Teenager With Xeroderma Pigmentosum and Trichothiodystrophy Overlap.
1/2019Mortality-associated immunological abnormalities in trichothiodystrophy: correlation of reduced levels of immunoglobulin and neutrophils with poor patient survival.
4/2016GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy.
3/2015Mutations in the TTDN1 gene are associated with a distinct trichothiodystrophy phenotype.
8/2013Abnormal XPD-induced nuclear receptor transactivation in DNA repair disorders: trichothiodystrophy and xeroderma pigmentosum.
12/2011Ocular manifestations of trichothiodystrophy.
10/2008Persistence of repair proteins at unrepaired DNA damage distinguishes diseases with ERCC2 (XPD) mutations: cancer-prone xeroderma pigmentosum vs. non-cancer-prone trichothiodystrophy.

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Sikandar G Khan Research Topics

Disease

17Xeroderma Pigmentosum (Kaposi's Disease)
10/2021 - 06/2002
9Neoplasms (Cancer)
04/2014 - 08/2002
8Skin Neoplasms (Skin Cancer)
10/2021 - 02/2004
7Trichothiodystrophy Syndromes
10/2021 - 10/2008
4Melanoma (Melanoma, Malignant)
05/2014 - 06/2005
3Inborn Genetic Diseases (Disease, Hereditary)
10/2021 - 11/2013
3Cockayne Syndrome (Syndrome, Cockayne)
10/2021 - 06/2002
2DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
09/2013 - 01/2009
1Reinfection
10/2021
1Hepatitis
10/2021
1Multiple Endocrine Neoplasia Type 1
07/2021
1Premature Aging
10/2019
1Ototoxicity
04/2015
1Complementation Group C Xeroderma Pigmentosum
04/2015
1Nevus (Nevi)
05/2014
1Deafness (Deaf Mutism)
09/2013
1Cachexia
05/2013
1Atrophy
05/2013
1HELLP Syndrome
12/2012
1Hemolysis
12/2012
1Pre-Eclampsia (Preeclampsia)
12/2012
1Dry Eye Syndromes (Dry Eye Syndrome)
12/2011
1Macular Degeneration (Age-Related Maculopathy)
12/2011
1Birth Weight (Birth Weights)
11/2011
1Cryptorchidism (Undescended Testes)
11/2011
1Hypersensitivity (Allergy)
01/2009
1Complementation Group G Xeroderma Pigmentosum
06/2002
1Neurologic Manifestations (Neurological Manifestations)
06/2002

Drug/Important Bio-Agent (IBA)

6DNA (Deoxyribonucleic Acid)IBA
10/2021 - 01/2009
3SulfurIBA
03/2015 - 12/2011
3Proteins (Proteins, Gene)FDA Link
10/2008 - 06/2002
2A-Form DNA (A-DNA)IBA
10/2019 - 11/2006
2Messenger RNA (mRNA)IBA
01/2006 - 02/2004
2RNA IsoformsIBA
06/2005 - 08/2002
1Anti-Bacterial Agents (Antibiotics)IBA
10/2021
1Metronidazole (Metric)FDA LinkGeneric
10/2021
1Fumarate Hydratase (Fumarase)IBA
07/2021
1Immunoglobulins (Immunoglobulin)IBA
01/2019
1Transcription Factors (Transcription Factor)IBA
04/2016
1transcription factor TFIIE (TFIIE)IBA
04/2016
1Pharmaceutical PreparationsIBA
04/2015
1Gentamicins (Gentamicin)FDA LinkGeneric
04/2015
1Therapeutic UsesIBA
04/2015
1antibiotic G 418IBA
04/2015
1Terminator Codon (Termination Codon)IBA
04/2015
1AminoglycosidesIBA
04/2015
1Nonsense Codon (Nonsense Mutation)IBA
11/2013
1Tumor Suppressor Protein p14ARF (p14ARF)IBA
09/2013
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
08/2013
1EnzymesIBA
12/2012
1Retinaldehyde (Retinal)IBA
12/2011
1Fluorescein (Funduscein)FDA LinkGeneric
12/2011
1Collodion (Nitrocellulose)IBA
11/2011
1RNA Precursors (Precursor, mRNA)IBA
02/2010
1U2 Small Nuclear RibonucleoproteinIBA
02/2010
1Amino AcidsFDA Link
04/2009
1PyrimidinesIBA
04/2009
1Initiator Codon (Start Codon)IBA
01/2009
1DNA HelicasesIBA
11/2006
1Transcription Factor TFIIHIBA
11/2006
1Complement System Proteins (Complement)IBA
06/2002

Therapy/Procedure

2Lasers (Laser)
05/2014 - 04/2009
1Aftercare (After-Treatment)
10/2021
1Protective Clothing
04/2014
1Therapeutics
11/2013
1Denervation
05/2013